Vanessa became a mercenary herself, eventually employed by arms dealer Tolliver, who had her impersonate the mercenary Domino so as to spy on Cable, even joining Cable's new X-Force strike team.
That night, Wilson broke up with Vanessa after learning he had cancer, leaving her heartbroken. Vanessa Carlysle was soon saved from Wilson's vengeful employers by Zoe Culloden, a time-traveling agent of Landau, Luckman & Lake who had journeyed into the past to prevent Wilson's eventual self-destruction.
Vanessa and WadeYoung mutant shape-shifter Vanessa Carlysle fell into a life of prostitution in Boston, where she met and fell in love with mercenary Deadpool (Wade Wilson).
